Page 6 - hypertension_newsletter (5)

REFLECTIONS rtensio n
Hypertension Global Newsletter #2 Hype
Hype

n oisnetr

Dots indicate mean values, error bars indicate SDs, lines indicate fitting smoothing spline curves with 95% Cis in gray. Trajectories over time have been obtained with
latent variable analysis.

CLINICAL PEARLS FROM THE FACULTY Based on exploratory findings of the SPARTE study, the
reduction of primary outcome may be more significant in
WATCH very high risk patients or those with an elevated PWV above
PROF. LAURENT DISCUSS HIS THOUGHTS expected for age. The results from the SPARTE study can
ON THE RELEVANCE OF THE SPARTE be considered as exploratory ones to plan larger, adequately
STUDY TO CLINICAL PRACTICE. powered studies aimed at demonstrating the effectiveness of
a PWV-based rather than a BP-based strategy in patients with
primary hypertension.

CLICK HERE
FOR THE LINK TO FULL ARTICLE

ADHERENCE

Adherence to single-pill versus free-equivalent combination therapy in
hypertension: A systematic review and meta-analysis.

Parati G, et al. Hypertension. 2021;77(2):692-705.

Poor adherence to antihypertensive therapy remains a global challenge and a major cause of poor BP control in patients
with hypertension. This systematic review and meta-analysis aimed to review whether simplification of the treatment regimen
through single-pill combination (SPC) led to improved adherence, persistence, and better BP control compared with free-
equivalent combination (FEC).

TABLE OF CONTENTS